Neuromuscular disease is a broad term that encompasses many diseases and ailments that impair the functioning of the muscles, either directly, as pathologies of the voluntary muscle, or indirectly, as pathologies of nerves or neuromuscular junctions.
July 07, 2010
Q&A: Mechanism Of Action Of Metformin
Initial treatment of patients with type 2 diabetes mellitus includes lifestyle changes focusing on diet, increased physical activity and exercise, and weight reduction, reinforced by consultation with a registered dietitian and diabetes self-management education, when possible.
July 06, 2010
Q&A: Vascular Complications Of Cytotoxics: Hepatic Veno-Occlusive Disease
Anticancer drugs have improved mortality rates and 5-year survival rates in patients with cancer, however, many of the modern chemotherapies are associated with cardiovascular toxicities that increase cardiovascular risk in cancer patients, including the development of hepatic veno-occlusive disease in certain cases.
Q&A: Management of Sleep Apnoea
The most common sleep disorder is insomnia. Others are sleep apnea, narcolepsy and hypersomnia (excessive sleepiness at inappropriate times), sleeping sickness (disruption of sleep cycle due to infection), sleepwalking, and night terrors.
July 05, 2010
Q&A: Vascular Complications Of Cytotoxics: Thrombosis and Thromboembolism
Development of new anticancer drugs has resulted in improved mortality rates and 5-year survival rates in patients with cancer. However, many of the modern chemotherapies are associated with cardiovascular toxicities that increase cardiovascular risk in cancer patients, including hypertension, thrombosis, heart failure, cardiomyopathy, and arrhythmias. These limitations restrict treatment options and might negatively affect the management of cancer.
July 04, 2010
Q&A: Drug-Induced Torsades de Pointes
Torsades de pointes is a distinctive polymorphic ventricular tachycardia in which the QRS amplitude varies and the QRS complexes appear to twist around the baseline. Torsades de pointes is associated with a prolonged QT interval, which may be congenital or acquired.
July 03, 2010
Overcoming Low Life Expectancy in Africa: How to live longer and healthier
When this article was first written in July 2010, official figures for life expectancy in most African countries were at record low levels, for example Nigeria had a life expectancy of 47 years. Since then, it appears some countries in Africa have worked to improve life expectancy impressively, while others continue to decline including Nigeria which I used as an example in the original article.
Fever: Classes, Causes and Treatment
Fever, also called pyrexia, is abnormal rise in body temperature of a person above the normal level. Fever itself is not an illness. A fever is a symptom of an underlying condition, most often an infection, but may also occur in an inflammation or even tumour.
Q&A: Complement Deficiencies
The complement system is a major component of innate immunity and a "complement" (from which its name is derived) to antibody-triggered responses. It consists of nearly 60 plasma and membrane proteins that form three distinct but overlapping activating pathways, as well as a common terminal lytic cascade and a network of regulators and receptors.
Secret to long and healthy living
WITH official figures of life expectancy in most African countries at low levels eg Nigeria is 47years, it implies that those who are above 50 in the country deserve a thanksgiving celebration.
July 01, 2010
Q&A: Asthma Control in Children
Asthma is a common chronic inflammatory condition of the airways, associated with airway hyperresponsiveness and variable airflow obstruction. The most frequent symptoms of asthma are cough, wheeze, chest tightness, and breathlessness.
Vermiform Appendix: Useful and in fact Promising
The body's appendix has long been thought of as nothing more than a worthless evolutionary artifact, good for nothing save a potentially lethal case of inflammation.
Q&A: Pharmacologic Stress Echocardiography
Stress echocardiography (echo) is an established technique for assessing coronary artery disease. It has been used for diagnosis and assessment of probable coronary artery disease, for risk stratification and to guide revascularisation procedures.
Antiretroviral Therapy for HIV/AIDS
Standard highly active antiretroviral therapy (HAART) consists of the use of at least three antiretroviral (ARV) drugs to maximally suppress the HIV virus and stop the progression of HIV disease.
Parkinson's Disease: Frequently Asked Questions
Parkinson's disease (PD) is a long-term degenerative disease of the central nervous system that mainly affects the motor system, and the symptoms generally come on slowly over time. With a diagnosis of such a life-changing medical condition, you may feel angry, afraid, sad, or worried about what lies ahead. Medical Notes has compiled a list of possible frequently asked questions (FAQs) you may have.
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